SECOND ANNUAL MEETING PHASE 3 (1999)

FROM GENES TO THERAPIES

TUESDAY APRIL 20 - FRIDAY APRIL 20, 1999


Blue Mountain Resort

RR #3 Collingwood, Ontario, L9Y 3Z2

Tel: 705-445-0231; Fax: 705-444-1751

www.bluemountain.ca


TUESDAY, APRIL 20


18:00

ARRIVE HOTEL - check-in, poster set-up and settle

 

19:00 - 20:30

DINNER

INN CAFE

20:30

WELCOME: MICHAEL HAYDEN

WEIDER ROOM

20:40

WELCOME: RON WOZNOW

WEIDER ROOM

20:45 - 21:15

KEYNOTE SPEAKER: JEREMY CARVER, CEO, GLYCODESIGN Inc.

WEIDER ROOM

 

Lessons for Scientists setting up your own Company

 

21:30

NIGHT OWL SOCIAL - poster set-up

 


WEDNESDAY, APRIL 21


07:00 - 08:00

BREAKFAST BUFFET

INN CAFE

08:00 - 11:20

SYMPOSIUM 1: STUDIES IN PATHOGENESIS

WEIDER ROOM

 

Facilitator: Bob Korneluk (CHEO)

 

08:00

Philip Marshall (OGH): Role of the dystrophin enhancer in vivo

 

08:20

Michael Rudnicki (McMasterU): Severe strain dependent phenotypes of mice lacking the retinoblastoma-related p107 and p130 genes

 

08:40

David MacLennan (UofT): Pathophysiological differences between Malignant Hypothermia and Central Core Disease

 

09:00

Brian Robinson (HSC): Mitochondria and Oxygen free radicals in disease

 

09:20

Rima Rozen (MCH): Genetics of MTHFR deficiency and generation of mouse model

 

09:40

Elise Heon (UofT): The gamma crystallins and human cataract: a puzzle made clearer

 

10:00 - 10:20

Break

 

10:20

Frank Jirik (UBC): Fibrillin-1 mutation responsible for the tight-skin phenotype?

 

10:40

Alex Mackenzie (UofO): Analysis of NAIP: The story so far.

 

11:00

Michael Hayden (UBC): Cleavage of huntingtin: A crucial step in pathogenesis

 

11:20 - 12:30

ATTENDED POSTER SESSION 1: Pathogenesis & Functional Genomics, Genetic Therapies and Genetics & Health Care Posters

WIEDER ROOM

12: 30 - 14:00

LUNCH

INN CAFE

14:00 - 15:00

PLENARY SESSION

WEIDER ROOM

14:00

Michael Hayden (CMMT): "State of the Network"

 

14:30

Anthony Pawson (SLRI): "Mapping the protein wiring diagram of the cell"

 

15:00 - 17:00

CONCURRENT WORKSHOP 1: BIOINFORMATICS

WEIDER ROOM

 

Facilitator: Francis Ouellette

 

15:00

Jamie Cuticchia (HSC): Map Information and High Performance Computing at HSC

 

15:30

Francis Ouellette (CMMT): Databases and Bioinformatics Resources & Training

 

16:00

Chris Hogue (SLRI): BIND: A new database

 

16:30

Discussion led by Francis Ouellette

 

15:00 - 16:30

CONCURRENT WORKSHOP 2: CREATING YOUR OWN COMPANY

SPECTACULAR ROOM

15:00

Ron Woznow (CGDN): Introduction

 

15:15

Sam Milstein (Emisphere) - "Start-up Company Dilemma - Science vs. The Product"

 

15:30

John Clement (BioChem Pharma)

 

15:45

Roundtable Q&A session (45 minutes)

 

16:30

PRIORITIES & PLANNING COMMITTEE MEETING (P&P members only)

SENATOR I ROOM

18:30 - 20:00

DINNER

INN CAFE

 

 

 

20:00 - 21:00

CONCURRENT SESSION: PRINCIPAL INVESTIGATOR NETWORKING SESSION

- CIHR DISCUSSION

Ron Worton (OGH) & Colin Goodfellow (MRC)

WEIDER ROOM

20:00 - 21:00

CONCURRENT SESSION: TRAINEE NETWORKING SESSION

Facilitators: Abigail Hackham (UBC)& Andy Boright (HSC)

SPECTACULAR ROOM


THURSDAY, APRIL 22


07:00 - 08:00

BREAKFAST BUFFET

INN CAFE

08:00 - 11:20

SYMPOSIUM 2: GENE IDENTIFICATION

WEIDER ROOM

 

Facilitator: Philippe Gros (McGill)

 

08:00

Robert Hegele (Robarts Inst): Diabetes in the Aboriginal Canadian Population

 

08:20

Rod McInnes (HSC): Mutations in the Chx10 homeobox gene cause microphthalmia in man

 

08:40

Guy Rouleau (MGH): The genetics of suicide

 

09:00

Francois Rousseau (Laval): Population genetics of FMR1 gene mutations reveal that loss of an AGG interruption occurs late in process of expansion

 

09:20

David Dyment (LHSC): The Major Histocompatability Complex and Multiple Sclerosis

 

09:40

Steve Scherer (HSC): Lafora's Progressive Myoclonus Epilepsy

 

10:00 - 10:20

Break

 

10:20

Peter St. George-Hyslop (UofT): Genetics of Alzheimer disease

 

10:40

Barb Triggs-Raine: The role of hGrb14 in insulin signalling

 

11:00

Rachel Wevrick (UofA): The genetics of Prader-Willi syndrome: candidate genes for obesity and behaviour

 

11:20 - 12:30

ATTENDED POSTER SESSION 2: Gene Identification Posters

WEIDER ROOM

12:30 -14:00

LUNCH

INN CAFE

14:00 - 15:00

ATTENDED POSTER SESSION 3: Core Facilities

WEIDER ROOM

15:00 - 18:00

WORKSHOP 3: CHIP TECHNOLOGY

Co-chairs: Jim Woodgett (OCI) & Tom Hudson (MGHRI)

WEIDER ROOM

15:00

Jim Woodgett (OCI): Overview of microarrays & applications

 

15:45

Todd Golub (Whitehead): Finding patterns in complex gene expression data

 

16:15

Marcel Behr (McGill): Comparative genomics of BCG vaccines by whole genome DNA microarray

 

16:45

Bryan McNeil (OCI): Developments of the Toronto microarray consortium

 

17:15

Rod McInnes (HSC): Using cDNA arrays to determine the molecular and biochemical basis premature neuronal cell death

 

17:30

PANEL DISCUSSION Led by Tom Hudson (MGHRI)(45 minutes)
Questions can be sent in advance of the session to [email protected]

 

18:30 - 20:30

BANQUET DINNER

INN CAFE

20:30 - 22.00

WORKSHOP 4: CONFLICTS OF INTEREST IN GENETICS RESEARCH

Facilitator: Brenda Gallie (HSC)

WEIDER ROOM

20:30

Brenda Gallie (HSC): Introduction

 

20:35

Arthur Schafer (University of Manitoba): When scientists wear two hats: the problem of competing interests

 

21:15

Dr. Frances Rolleston (MRC)

 

21:30

Discussion led by Brenda Gallie (HSC) (30 minutes)

 


FRIDAY, APRIL 23


07:00 - 08:00

BREAKFAST BUFFET

INN CAFE

8:00 - 9:00

KEYNOTE SPEAKER: PETER GOODFELLOW (SMITH KLINE BEECHAM PLC)

PRESENTATION FOR BEST POSTERS

WEIDER ROOM

09:00 - 12:00

SYMPOSIUM 4: GENETICS THERAPIES

Facilitator: Charles Scriver (MCHRI)

WEIDER ROOM

09:00

Pieter Cullis (UBC): Stabilized plasmid-particles for systemic gene therapy

 

09:20

Phil Hieter (UBC): Identification of yeast and human checkpoint responsive genes by transcriptional profiling

 

09:40

Steve Narod (UofT): Risk factors in contralateral BRCA1 /2 carriers

 

10:00 - 10:30

Break

 

10:30

Jeremy Squire (OCI): Molecular Cytogenetic Analysis of Genetic Changes Associated with Solid Tumour Progression

 

10:50

Charles Scriver (MCH): PAL and the treatment of PKU

 

11:10

Lap-Chee Tsui (HSC): HVJ-based Cystic Fibrosis Gene Therapy

 

11:30

Bob Korneluk: IAP: Gene therapy in neurodegeneration

 

11:50

Closing Remarks

 

12: 00 - 13:15

LUNCH

INN CAFE

13:15 - 14:00

CGDN INC: ANNUAL GENERAL MEETING

INN CAFE

15:00

BUSES DEPART