What are
Genetic Diseases?
| Genetics is the transmission of biological information from one generation to the next. Genes are units of biological information which are used by cells and organs to determine the development and function of the human body. Genetic variation among individuals means that each of us has a unique genetic make-up that influences our susceptibility to disease. |
| Genetic diseases are caused by changes or mutations in the body's genes. These mutations may be inherited from previous generations or occur in the cells of an individual's body. Single mutations in critical parts of genes can lead to onset of disease. Combinations of genes are implicated in many common diseases not usually classed as genetic, and genetic predispositions can result in disease if triggered by environmental factors. |
| Approximately 60% of Canadians will develop or die from a disease with a significant genetic component. Over 50% of children admitted to paediatric hospitals are admitted because of genetically-transmitted illnesses. The scientists and physicians of the Canadian Genetic Diseases Network, located at universities and medical centres across Canada, are making great strides in genetic research and have received national and international recognition. Canadian industry and venture capital organizations are responding to these scientific advances by forming partnerships and new ventures to develop new diagnostics and therapies, based on Network research. |
Suggested reading:
Genetics in Canadian Health Care
: Report 42 of the Science Council of Canada, 1991
(copies from Communications Canada,
catalogue no. SS 22-1991/42E, tel.(819-956-4802))
The Gene Machine, Gordon Hutchinson, MD
: Trek Magazine of Emerging Technology, Feb./Mar., 1992.
The Fight for Life: a Genetic Revolution
: Maclean's, July 15, 1991.
On the leading edge: Canadians are at the forefront of diabetes research
: Maclean's, Oct. 31, 1994.
Diabetes: a disease, a metabolic disorder
: the Globe & Mail, Nov. 1, 1996, Section C.
An Alzheimer's Clue
: Maclean's, July 10, 1995.
