Comprehensive and up-to-date access to available ES cell mutations on the EScells.ca website (http://www.EScells.ca)
"Hot List" service
CGDN members can submit their requests by email directly to Geoff Hicks ([email protected]). Requests will automatically be queried against each new database update.
ES cell lines
service charge to defray the cost of expanding the clone, verifying the mutation and shipping.
Generation of knockout mice to obtain specific ES cell mutations
initial ES cell characterization services (eg confirm gene-specific mutation, confirm preliminary "competency" tests of ES cells prior to injection, and help derive mutation specific probes and assays).
blastocyst injections or germline transmission of the ES cell mutations, pronuclear injection and/or homologous recombination and tetraploid aggregations.
On site training of members from other CGDN laboratories.
Contact and Submission:
For more information on the CGDN Functional Genomics Core Facility, please contact:
Dr. Geoff Hicks
CGDN Functional Genomics Core Facility
Manitoba Institute of Cell Biology,
675 McDermott Avenue
Winnipeg, MB R3E 0V9
Phone: (204) 787-2133
Fax: (204) 787-2190
Email: [email protected]