17:00-18:00

ARRIVE HOTEL - check-in, poster set-up and settle

19:00 - 20:30

DINNER (Everest A)

20:30 - 21:55

WELCOME SESSION (Everest B)

20:30

MICHAEL HAYDEN (Scientific Director, CGDN): Welcome

20.50

RON WOZNOW (CEO, CGDN):  2005 and beyond

21:10

Motivational Speaker: Anne Wheeler (Canadian film producer)

21:55

NIGHT OWL SOCIAL and poster set-up (Edelweiss & St. Moritz)

07:00 - 08:00

BREAKFAST BUFFET (Everest A)

08:00 - 9:40

SESSION 1: GENE THERAPY AND HEALTH CARE (Everest B)
Facilitator: Celia Greenwood

08:00 - 08:20

Lorne Clarke :  Clinical trial of human recombinant iduronidase inMPS I:  From the bench to the bedside

08:20 - 08:40

Steven Narod:  Oral contraceptives and the risk of breast cancer in carriers of BRCA1 and BRCA 2 mutations: an international study

08:40 - 09:00

Andrew Paterson:  The genetics of type I diabetes and related complications

09:00 - 09:20

David MacLennan: The role of phospholamban mutations in cardiac contractility and cardiomyopathy

09:20 - 09:40

Charles Scriver: Progress with the PKU/PAL/PAH project - in various amusing details

09:40 - 10:00

Coffee Break

10:00 - 12:00

SESSION 2:  PATHOGENESIS AND FUNCTIONAL GENOMICS (Everest B)                                                                                                                                          Facilitator: François Rousseau

10:00 - 10:20

Elise Heon:  Anterior segment genes and human vision

10:20 - 10:40

Tom Hudson: Regulatory genetics

10:40 - 11:00

Andras Nagy:  The current progress of nuclear transfer cloning and superior developmental potential of F1 hybrid ES cells

11:00 - 11:20

Brenda Gallie: Diversity of the SMART mammalian expression system

11:20 - 11:40

Ekaterina Rogaeva: A Novel PS1 Case of Variant Alzheimer's Disease with Spastic Paraparesis: The Search for a Gene-Modifier

11:40 - 12:00

Alex MacKenzie: FONA: Fiber optic based gene profiling; it's application to disease diagnosis and drug discovery

12:00-13:30

Lunch (Everest A)

12:00 - 13:30

PRIORITIES & PLANNING COMMITTEE (P&P members only - Chamonix A)

13:30 - 15:10

SESSION 3:  GENE IDENTIFICATION (Part 1) (Everest B)                                                                                                                          Facilitator: Dennis Bulman

13:30 - 13:50

Moira Glerum:  The cytochrome oxidase assembly pathway:  Are we there yet?

13:50 - 14:10

Rod McInnes:  Neto1 and Neto2, a novel neuronal receptor protein family essential for neurodevelopment and perhaps memory

14:10 - 14:30

Philippe Gros: Complex genetic control of susceptibility to malaria in mice

14:30 - 14:50

Brian Robinson:  Gene responsible for one form of mitochondrial complex I deficiency locates by chromosome transfer to the X-chromosome

14:50 - 15:10

Mike Walter: Protein localization in the human eye and genetic screen of opticin, a candidate modifier of age-related macular degeneration.

15:10 - 16:00

Break & Attend Poster Session I (Edelweiss & St. Moritz)

Genetics Outreach Committee (C’tee members only: Chamonix A)

16:00 - 17:40

SESSION 4:  HOT NEW RESEARCH  (Everest B)                                                                                                                              Facilitator: Lap-Chee Tsui

16:00 - 16:20

Christopher Pearson: In vitro trinucleotide repeat instability by human cell extracts

16:20 - 16:40

John Dick: Discovery of novel classes of human hematopoietic stem cells

16:40 - 17:00

Bob Korneluk: Inhibitor Apoptosis Protein (IAP) as cancer targets - Why it works

17:00 - 17:20

Steve Scherer:  Annotation of human chromosome 7 for discovery of new genes and disease mechanisms

17:20 - 17:40

Robin Hsiung:  Linkage analysis in Dyslexia - Update on Chr 11p

17:40 - 18:30

Break & Attend Poster Session II (Edelweiss & St. Moritz)

18:30 - 20:00

Dinner (Everest A)

20:00 - 21:30

SESSION 5: ETHICAL ISSUES IN SCIENCE - PANEL DISCUSSION (Everest B)

Keynote for discussion: Michael Hayden

20:00 - 20:45

Topic #1: The Rare Resource: Obligations to share published reagents ormaterials

20:45 - 21:30

Topic #2: Obligations in exchange for materials received

07:00 - 08:00

BREAKFAST BUFFET (Everest A)

08:00 - 10:00

SESSION 6: HOT RESEARCH IN INDUSTRY  (Everest B)
Facilitator: Guy Rouleau

08:00 - 08:20

Michael Phillips (Orchid BioSciences):  On the road to Genome-wide SNP map 

08:20 - 08:40

Ian MacLachlan (Protiva Biotherapeutics):  Development of Non-viral Gene Transfer Systems for Cancer, Inflammation and Other Genetic Diseases

08:40 - 09:00

Mike Moran (MDS Proteomics):  Using proteomics to make decisions in drug discovery

09:00 - 09:20

Paul Goldberg ( Xenon Genetics): From Dreams to Drugs - Using Mice and Men to Discover Novel Validated Drug Targets

09:20 - 09:40

Michael Dennis (SignalGene): SignalGene: Converting Targets into IND Candidates 

09:40 - 10:00

John Gillard (Aegera Therapeutics): Title TBA

10:00 - 11:00

Break & Attend Poster Session III (Edelweiss & St. Moritz)

11:00- 12:00

Michael Hayden & Ron Woznow:  The future of CGDN (Everest B)

12:00 - 14:00

CGDN Annual General Meeting & Lunch (Everest A)                                                                                                      

14:00 - 15:00

SESSION 7:  NEW TECHNOLOGIES (Everest B)                                                                                                                           Facilitator:  Daniel Sinnett

14:00 - 14:20

Francis Ouellette:  Bioinformatics resources for CGDN users

14:20 - 14:40

Robert Nadon (Imaging Research Inc.):  Statistical issues with cDNA and Affymetrix Microarrays: Processing and analysis

14:40 - 15:00

Jim Woodgett (Ontario Cancer Institute):  Practical considerations for the application of microarrays to analysis of disease

15:00 - 17:00

Individual Networking Sessions

17:00 - 18:30

Attend Poster Session IV (Edelweiss & St. Moritz)

19:00 - 21.30

BANQUET (Everest A)

Canadian Gene Cure Foundation - Jeans for Genes Day awards: The Right Honourable Ramon Hnatyshyn

Dinner Speaker - Stuart Ellis-Myers: How to communicate more effectively….and actually enjoy the process

07:00 - 08:00

BREAKFAST BUFFET (Everest A)

08:00 - 10:00

SESSION 8: GENE IDENTIFICATION (Part 2) (Everest B)

Facilitator:  Rima Rozen

08:00 - 08:20

Rachel Wevrick:  The complex genetics of Prader-Willi Syndrome:  The role of the necdin/MAGE gene family

08:20 - 08:40

Stephen Meyn:  Cancer instability syndrome

08:40 - 09:00

Robert Hegele:  An update on genes for type 2 diabetes

09:00 - 09:20

Diane Cox:  A new gene for copper transport causes canine copper toxicosis

09:20 - 09:40

Erwin Schurr : Genetic factors in susceptibility to leprosy and primary tuberculosis

09:40 - 10:00

Pierre Chagnon: Cloning the gene for the North American Indian Childhood Cirrhosis

10:00 - 10:15

Coffee Break

10:15- 11:30

SESSION 9: RESEARCH ADVANCES (Student/Post-doc presentations) (Everest B)
Facilitators: Geoff Hicks

10:15 - 10:30

Peter Lee: Decision tree inference of gene interaction networks from gene expression profiles of recombinant congenic strains

10:30 - 10:45

Melissa Dobson: Identification of the gene responsible for a disorder of vitamin B12 utilization based on the analysis of prokaryotic gene arrangements

10:45 - 11:00

Eduardo Diez: Identification of the Natural Host Defense Locus Lgn1

11:00 - 11:15

Roshni Singaraja:  Increases in ABCA1 expression confers significant protection against atherosclerosis

11:15-11:30

Kendra Cann: Nucleolar association of TLS, a novel DNA-damage response protein

11:30-11:45

Wrap Up

11:45 - 12:45

Lunch (Everest A)

13:30

Buses depart for flights to Toronto and London

15:00

Buses depart for flights to Vancouver, Calgary, Edmonton and Winnipeg